Книги
  • @
  • «»{}∼
Replicative Cessation & DNA Damage in Human Fibroblast under Stress

Replicative Cessation & DNA Damage in Human Fibroblast under Stress

31915533
7678 руб.
Добавить в корзину
Описание
Aging can be viewed partly as a degenerative process dictated by free radical reactions. Human diploid fibroblasts (HDFs) lose the capacity to proliferate and enter a state termed replicative senescence after a finite number of population doublings in vitro. Presenescent human fibroblasts, when treated with a sub-lethal dose of H2O2, enter long term growth arrest resembling replicative senescence. H2O2 induced growth arrest; p53 protein expression and the effect of vitamin C as an antioxidant were determined in this study.
A study to investigate the replicative cessation, morphology and DNA damage in human fibroblasts under stress conditions